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RGF1 Key Research Highlights
Arsenic is a ubiquitous toxicant to the Southwestern population due to exposure via drinking water, dust, and ingestion. Arsenic is a known human carcinogen causing cancer at various sites and has a multitude of toxic effects.
In vivo studies investigated the role of arsenite and high fat diet in the metabolic profile in an outbred strain of mice, Swiss Webster. Of relevance to human arsenic exposures, groups of mice were treated with arsenic in utero and post-natally.
Human exposure to DBP occurs daily as evidenced by the detection of its metabolites in spot human urine samples from subjects in the National Health and Nutrition Examination Survey (NHANES).